C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) A61K 31/712 (2006.01) A61P 17/00 (2006.01) A61P 29/00 (2006.01) C07H 21/02 (2006.01)
Patent
CA 2357950
This patent describes the invention of a series of novel therapeutic oligonucleotide polymers targeted at inhibiting expression of genes coding for Phosphodiesterase 4. They are useful as analytical tools in the study of individual PDE isoforms and in the therapeutic treatment of depression, thrombosis, cystic fibrosis, gastric lesions, pulmonary hypertension, glaucoma, multiple sclerosis, atopic dermatitis, asthma and other allergic disorders as well as other illnesses in which an increase of cyclic AMP or a decrease in phosphodiesterase levels is useful.
L'invention concerne une série de nouveaux polymères oligonucléotidiques thérapeutiques destinés à inhiber l'expression de gènes codant pour la phosphodiestérase 4. Ces polymères oligonucléotidiques thérapeutiques peuvent être utilisés comme outils d'analyse pour l'étude d'isoformes PDE individuelles et pour le traitement de la dépression, de la thrombose, de la mucoviscidose, de lésions gastriques, de l'hypertension pulmonaire, du glaucome, de la sclérose en plaques, de la dermatite atopique, de l'asthme et autres troubles allergiques, ainsi que d'autres maladies dans lesquelles une augmentation de l'AMP cyclique ou une diminution des niveaux de la phosphodiestérase est utile.
Arrow Amy
Dale Roderic M. K.
Thompson Terry
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Lakewood-Amedex Inc.
Oligo Therapeutics Inc.
LandOfFree
Therapeutic phosphodiesterase inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Therapeutic phosphodiesterase inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Therapeutic phosphodiesterase inhibitors will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1922351