Therapeutic polypeptides, nucleic acids encoding same, and...

Details Therapeutic polypeptides, nucleic acids encoding same, and... Therapeutic polypeptides, nucleic acids encoding same, and...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 9/00 (2006.01) C12P 21/02 (2006.01) C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2465239

Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

L'invention se rapporte à de nouveaux polypeptides, et à des acides nucléiques les codant, présentant des propriétés de stimulation de réponses biochimiques ou physiologiques dans une cellule, un tissu, un organe ou un organisme. Plus précisément, ces nouveaux polypeptides sont des produits géniques de nouveaux gènes, ou des fragments déterminés biologiquement actifs ou des dérivés de ces derniers. L'invention concerne aussi des méthodes d'utilisation regroupant des procédés d'analyse diagnostique et pronostique, ainsi que des méthodes de traitement de différentes conditions pathologiques.

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