Therapeutic polypeptides, nucleic acids encoding same, and...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/11 (2006.01) A61K 38/17 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C12N 9/00 (2006.01) C12N 15/12 (2006.01) C12N 15/52 (2006.01) C12N 15/63 (2006.01) C12P 21/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2446427

Disclosed herein are nucleic acid sequences that encode G-coupled protein- receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the-polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

L'invention concerne des séquences d'acide nucléique codant des polypeptides associés au récepteur couplé à la protéine G. L'invention concerne également des polypeptides codés par lesdites séquences d'acide nucléique, des anticorps qui se lient au polypeptide de façon immunospécifique, ainsi que des dérivés, variants, mutants, ou des fragments du polypeptide, polynucléotide, ou anticorps concernés. L'invention se rapporte en outre à des méthodes thérapeutiques, des méthodes diagnostiques et des méthodes de recherche permettant de diagnostiquer, traiter et prévenir des troubles impliquant un(e) quelconque de ces protéines et acides nucléiques humains.

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