Therapeutic polypeptides, nucleic acids encoding same, and...

Details Therapeutic polypeptides, nucleic acids encoding same, and... Therapeutic polypeptides, nucleic acids encoding same, and...

C - Chemistry, Metallurgy

07

K

C07K 1/00 (2006.01) C07K 14/47 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2448073

Disclosed herein are nucleic acid sequences that encode G-coupled protein- receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

L'invention concerne des séquences d'acide nucléique codant des polypeptides récepteurs couplés à la protéine G. L'invention concerne également des polypeptides codés par ces séquences d'acide nucléique et sur des anticorps qui se lient de manière immunospécifique à ce polypeptide, ainsi que sur des dérivés, des variants, des mutants, ou des fragments du polypeptide, du polynucléotide ou de l'anticorps précités. L'invention concerne enfin des procédés thérapeutique, diagnostique et de recherche destinés au diagnostic, au traitement et la prévention de troubles dans lesquels interviennent l'un quelconque de ces nouveaux acides nucléiques et de ces nouvelles protéines humaines.

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