Therapeutic polypeptides, nucleic acids encoding same, and...

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/04 (2006.01) C07H 21/02 (2006.01) C07K 14/00 (2006.01) C12N 15/00 (2006.01)

Patent

CA 2495563

Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

L'invention concerne des séquences d'acides nucléiques codant pour de nouveaux polypeptides. L'invention concerne également des polypeptides codés par lesdites séquences d'acides nucléiques, et des anticorps qui se lient de manière immunospécifique au polypeptide ainsi que des dérivés, des variantes, des mutants, ou des fragments du nouveau polypeptide, polynucléotide ou anticorps spécifiques dudit polypeptide. L'invention concerne, en outre, des vecteurs, des cellules hôtes, des anticorps et des méthodes de recombinaison permettant de produire lesdits polypeptides et polynucléotides ainsi que des méthodes permettant de les utiliser. L'invention concerne enfin des méthodes thérapeutiques, diagnostiques et de recherche à des fins de diagnostic, de traitement et de prévention de troubles impliquant l'un quelconque de ces nouveaux acides nucléiques et protéines humains.

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