A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/29 (2006.01) A61K 9/16 (2006.01) A61K 9/72 (2006.01) A61K 47/26 (2006.01)
Patent
CA 2206657
The present invention relates to compositions and methods for pulmonary administration of full-length parathyroid hormone to mammalian hosts for the treatment of osteoporosis. Thus there is provided a therapeutic preparation comprising a human full-length parathyroïd hormone, or homologues thereof, in the form of a dry powder suitable for inhalation in which at least 50 % of said dry powder consists of (a) particles having a diameter of up to 10 microns; or (b) agglomerates of such particles.
La présente invention concerne des compositions et des procédés d'administration pulmonaire de l'hormone parathyroïdienne complète à des mammifères hôtes, pour le traitement de l'ostéoporose. L'invention concerne donc une préparation thérapeutique comprenant une hormone parathyroïdienne humaine complète ou ses homologues, sous la forme d'une poudre sèche convenant à l'inhalation, et dans laquelle au moins 50 % de cette poudre sèche sont constitués par (a) des particules dont le diamètre va jusqu'à 10 microns; ou (b) des agglomérats de telles particules.
Backstrom Kjell
Wallmark Bjorn
Astra Aktiebolag
Astrazeneca Ab
Fetherstonhaugh & Co.
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