C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/00 (2006.01) A61K 39/395 (2006.01) C07K 16/06 (2006.01)
Patent
CA 2520820
The present invention relates to a method for the production and the selection of human or chimaeric or humanized antibodies or molecules that comprise the Fc region of human IgG, capable of modulating the activity of one or several particular Fc receptors, such as the triggering of inhibitory functions through the human type IIB receptors of IgG (FcgammaRIIB/CD32).
L'invention concerne une méthode de production et de sélection d'anticorps ou de molécules humains ou chimériques ou humanisés qui contiennent la région Fc de l'IgG humaine et sont capables de moduler l'activité d'un ou plusieurs récepteurs de Fc particuliers, comme le déclenchement de fonctions inhibitrices par les récepteurs de type IIB de l'IgG humaine (FcgammaRIIB/CD32).
Bihoreau Nicolas
Bourel Dominique
de Romeuf Christophe
Fridman Wolf Herman
Nony Emmanuel
Institut National de La Sante Et de La Recherche Medicale (inser
Laboratoire Francais Du Fractionnement Et Des Biotechnologies
Lfb Biotechnologies
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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