Therapeutic pyrrolidines

Details Therapeutic pyrrolidines Therapeutic pyrrolidines

C - Chemistry, Metallurgy

07

D

C07D 207/12 (2006.01) A61K 31/40 (2006.01)

Patent

CA 2622222

The present invention provides for compounds of Formula (I), and pharmaceutically acceptable salts thereof, wherein A, J, Z, and R20 have any of the values defined therefor in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of disorders and conditions including attention deficit hyperactivity disorder, neuropathic pain, urinary incontinence, generalized anxiety disorder, depression, schizophrenia, and fibromyalgia. Also provided are pharmaceutical compositions comprising one or more compounds of Formula (I) or pharmaceutically acceptable salts thereof.

L'invention concerne des composés de formule (I) et des sels pharmaceutiquement acceptables de ceux-ci, A, J, Z et R20 ayant une des valeurs définies dans les spécifications, les sels pharmaceutiquement acceptables pouvant servir d'agents dans le traitement de troubles et d'états comprenant le manque d'attention, l'hyperactivité, la douleur neuropathique, l'énurésie, l'anxiété généralisée, la dépression, la schizophrénie et la fibromyalgie. La présente invention porte également sur des compositions pharmaceutiques contenant un ou plusieurs composés de formule (I) ou des sels pharmaceutiquement acceptables de ceux-ci.

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