Therapeutic treatment of accelerated bone resorption

Details Therapeutic treatment of accelerated bone resorption Therapeutic treatment of accelerated bone resorption

A - Human Necessities

61

K

A61K 31/00 (2006.01) A61K 31/7076 (2006.01) A61P 19/08 (2006.01) A61P 19/10 (2006.01)

Patent

CA 2586845

The present invention concerns the use of an A3 adenosine receptor agonist (A3AR agonist) for treatment of accelerated bone resorption, particularly, inflammation induced bone resorption. Specifically, there is provided by the present invention a method and pharmaceutical composition for treatment of said condition, the A3AR agonist being formulated as a pharmaceutical composition which is administered to a subject having accelerated bone resorption. The invention also provides the use of A3AR agonist in the preparation of said pharmaceutical composition.

L'invention concerne l'utilisation d'un agoniste du récepteur d'adénosine A3 (agoniste de A3AR) pour le traitement de la résorption osseuse accélérée, plus particulièrement de la résorption osseuse induite par une inflammation. Plus spécifiquement, l'invention concerne un procédé et une composition pharmaceutique pour le traitement de cet état pathologique, l'agoniste de A3AR étant formulé en tant que composition pharmaceutique administrée à un sujet souffrant de résorption osseuse accélérée. L'invention concerne également l'utilisation de l'agoniste de A3AR dans la préparation de cette composition pharmaceutique.

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