Therapeutic treatment of clostridium difficile associated...

Details Therapeutic treatment of clostridium difficile associated... Therapeutic treatment of clostridium difficile associated...

A - Human Necessities

61

K

A61K 39/40 (2006.01) A61K 38/08 (2006.01) A61K 38/12 (2006.01) C07K 16/12 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2197714

The effective treatment of Clostridium difficile associated diseases, such as Clostridium difficile colitis, pseudomembranous colitis and antibiotic associated diarrhea, by administering an antibody having specific activity against Clostridium difficile colitis and toxins thereof alone or in combination with vancomycin, bacitracin or metronidazole is herein described as well as pharmaceutical compositions therefor.

L'invention concerne le traitement efficace des maladies associéss au Clostridium difficile, telles que le Clostridium difficile colitis, l'entérocolite muco-membraneuse et les diarrhées associées aux antibiotiques. Ce traitement consiste à administrer un anticorps exerçant une activité spécifique contre le Clostridium difficile colitis et des toxines de celui-ci, seul ou en association avec de la vancomycine, de la bacitracine ou du métronidazole. L'invention traite également des compositions pharmaceutiques pour ces derniers.

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