A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/36 (2006.01) A61K 38/10 (2006.01) A61P 7/00 (2006.01) A61P 7/04 (2006.01)
Patent
CA 2540986
The present invention provides methods and compositions for treating bleeding episodes. The methods are carried out by administering to a patient in need thereof a preparation comprising a factor XI polypeptide, in an amount effective for such treatment. The methods of the invention result in one or more of: reduced clotting time; enhancement of hemostasis; increase in clot lysis time; increase in clot strength; and/or increase in overall clot quality (OCQ) in said patient.
La présente invention concerne des méthodes et des compositions de traitement de saignements. Les méthodes consistent à administrer à un patient en ayant besoin une quantité efficace pour un tel traitement d'une préparation contenant un polypeptide du facteur XI. Les méthodes de l'invention réduisent le temps de coagulation, améliorent l'hémostase, augmentent le temps de lyse d'un caillot, augmentent la résistance du caillot, et/ou augmentent la qualité générale du sang coagulé (OCQ) chez ledit patient.
Bjerregaard Jensen Simon
Hansen Jens Jacob
Oestergaard Soeren
Roejkjaer Rasmus
Viuff Dorthe
Dimock Stratton Llp
Novo Nordisk Health Care Ag
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