Therapeutic use of phosphoryl-l-serine-n-acyl-sphingosine

Details Therapeutic use of phosphoryl-l-serine-n-acyl-sphingosine Therapeutic use of phosphoryl-l-serine-n-acyl-sphingosine

C - Chemistry, Metallurgy

07

F

C07F 9/113 (2006.01) A61K 31/66 (2006.01) C07F 9/09 (2006.01)

Patent

CA 2141557

2141557 9403178 PCTABS00030 The present invention relates to the therapeutical use of phosphoryl-L-serine-N-acyl-sphingosine composed of a mixture of compounds of formula (I) or (II), in which n = 6-16 and R means an acyl residue of a higher aliphatic acid having between 16 and 24 carbon atoms, the distribution of the values for n and R being those of a natural sphingomyelin. The invention also includes a novel process for the preparation of these compounds, as well as pharmaceutical preparations containing them as active ingredients.

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