Therapeutic use of selective pde10 inhibitors

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/44 (2006.01) A61K 31/472 (2006.01) A61P 25/18 (2006.01) A61P 25/22 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2382326

The invention provides a pharmaceutical composition and kit for treating certain neurologic and psychiatric disorders in mammals, including humans, comprising a selective PDE10 inhibitor. In particular, the invention relates to treatment of mood, movement, and anxiety disorders; psychosis; drug, for example alcohol, addiction; and disorders having as a symptom deficient cognition. The invention furthermore provides the use of papaverine as a selective inhibitor of PDE10.

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