Therapeutic uses for an aminosterol compound

Details Therapeutic uses for an aminosterol compound Therapeutic uses for an aminosterol compound

A - Human Necessities

61

K

A61K 31/575 (2006.01) C07J 41/00 (2006.01)

Patent

CA 2255856

A pharmaceutical composition includes, as an active ingredient, a compound according to formula 1436, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier or excipient. Various pharmaceutical products may be produced including this pharmaceutical composition. Such pharmaceutical products may be used for the treatment of cancers, such as leukemia; inflammation; arthritis; and viruses, such as HSV. Methods for using the pharmaceutical compositions also are described. In these methods, various diseases are treated or other body functions are activated or inhibited by administering an effective amount of the pharmaceutical composition. For example, inflammation, arthritis, herpes simplex virus, melanoma, and leukemia may be treated by administering an effective amount of the pharmaceutical compositions. Viral replication, weight gain, and growth factor production can be inhibited by administering an effective amount of these pharmaceutical compositions. Appetite can be suppressed by administering an effective amount of the pharmaceutical compositions, and a diuretic effect can be produced.

Composition pharmaceutique contenant, comme principe actif, un composé de la formule 1436, représenté dans la figure, ou un sel pharmaceutiquement acceptable de ce composé, ainsi qu'un vecteur ou excipient pharmaceutiquement acceptable. Divers produits pharmaceutiques contenant cette composition peuvent être obtenus, ces produits pouvant être utilisés pour traiter les cancers, tels que la leucémie; les inflammations; l'arthrite; et les virus, tels que l'HSV. Des procédés d'utilisation de ces compositions pharmaceutiques sont également décrits. Selon ces procédés, diverses maladies peuvent être traitées ou d'autres fonctions organiques activées ou inhibées par administration d'une dose efficace de la composition pharmaceutique. Les inflammations, l'arthrite, le virus herpès simplex, les mélanomes et la leucémie, par exemple, peuvent être traités par administration d'une dose efficace de ces compositions, lesquelles peuvent également, administrées en doses efficaces, inhiber la réplication virale, la prise de poids et la production de facteurs de croissance, freiner l'appétit et produire un effet diurétique.

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