Therapeutic uses of the hypervariable region of monoclonal...

C - Chemistry – Metallurgy – 12 – P

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C12P 21/08 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) A61K 51/10 (2006.01) C07K 16/30 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2072017

2072017 9109058 PCTABS00005 Therapeutic agents and methods for treating and diagnosing leukemia are provided. Such agents comprise monoclonal antibody M195, a polypeptide capable of binding to the antigen of M195, or a chimeric antibody such as a peptide, conjugated to a cytotoxic agent, e.g. a radioisotope or alone. Methods for delivering genetic information to a targeted cell is also provided.

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