Therapeutic vitamin-calcium combination in unitary galenic...

A - Human Necessities – 61 – K

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A61K 31/59 (2006.01) A61K 9/00 (2006.01) A61K 33/06 (2006.01)

Patent

CA 2200568

A therapeutical combination including elemental calcium and at least one vitamin D as the combined active principles, and further containing at least one dry and wet binder combined in a synergistic amount with at least one diluent, at least one binder and at least one lubricant, at least one of said diluent and said binder being a sweetener. The ratio of elemental calcium to vitamin D, expressed in mg of elemental Ca per IU of vitamin D, is advantageously 1-1.5, preferably 1.2-1.3.

Cette association thérapeutique comprend comme principes actifs associés du calcium sous forme élémentaire et au moins une vitamine D. Elle renferme en outre au moins un liant à sec et en milieu humide combiné en quantité synergique avec au moins un diluant, au moins un liant et au moins un lubrifiant, l'un au moins dudit diluant et dudit liant étant un édulcorant. Avantageusement, le rapport du calcium sous forme élémentaire à la vitamine D, exprimé en mg de Ca élément par UI de vitamine D, est compris entre 1 et 1,5, préférentiellement entre 1,2 et 1,3.

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