Therapeutical system for transdermal delivery of levonorgestrel

A - Human Necessities – 61 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 9/00 (2006.01) A61K 9/70 (2006.01) A61K 31/56 (2006.01) A61K 31/565 (2006.01)

Patent

CA 2294788

The invention relates to a physically and chemically stable therapeutical transdermal sytem (TTS) for transcutaneous delivery of levonorgestrel alone or further sex steroid hormones also over a long period. The inventive system is characterized in that it has good fixation properties and comprises a matrix containing polymethacrylate-based steroid hormones to be fixed by contact. The invention also relates to a method for producing such a system, advantageously characterized in that it does not contain any solvent and preserves the active agents. The inventive TTS is characterized in that it is physically and chemically stable, has good fixation properties over long periods and delivers across the skin large amounts of active agents per surface unit. One advantage of the inventive method of production is that said active agents are as little exposed to temperature stress as possible, resulting in minimized degradation or decomposition reactions.

La présente invention porte sur un système thérapeutique transdermique (STT) physiquement et chimiquement stable pour l'administration transcutanée de levonorgestrel seul ou d'autres hormones stéroïdes sexuelles pendant de longues périodes. Ce système présente de bonnes propriétés de fixation et est constitué d'une matrice à teneur en hormones stéroïdes à fixation par contact à base de polyméthacrylate. L'invention porte également sur un procédé de fabrication de ce système, qui a l'avantage de ne contenir aucun solvant et de bien préserver les principes actifs. Le STT selon l'invention se caractérise par sa stabilité physique et chimique, présente de bonnes propriétés de fixation sur de longues périodes et délivre à travers la peau de grandes quantités du principe actif par unité de surface. Le processus de fabrication présente, entre autres, l'avantage que les principes actifs sont aussi peu exposés à des contraintes thermiques que faire se peut, d'où une minimisation des réactions de dégradation ou de décomposition.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Therapeutical system for transdermal delivery of levonorgestrel does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Therapeutical system for transdermal delivery of levonorgestrel, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Therapeutical system for transdermal delivery of levonorgestrel will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1717615

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.