Therapeutically active triazoles and their use

Details Therapeutically active triazoles and their use Therapeutically active triazoles and their use

C - Chemistry, Metallurgy

07

J

C07J 43/00 (2006.01) A61K 31/58 (2006.01) A61P 5/32 (2006.01) A61P 13/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2663242

This invention relates to novel estratrien-triazoles of general formula (I) useful in therapy, especially for use in the treatment and/or prevention of a steroid hormone dependent disorder, preferably a steroid hormone dependent disease or disorder requiring the inhibition of a 17.beta.-hydroxysteroid dehydrogenase (17.beta.-HSD) such as 17.beta.-HSD type 1, type 2 or type 3 enzyme.

La présente invention concerne des estratriènes-triazoles innovantes de formule générale (I) utilisables pour une thérapie, en particulier pour le traitement et/ou la prévention d'une affection liée aux hormones stéroïdiennes, de préférence une maladie ou une affection liée aux hormones stéroïdiennes qui exige l'inhibition d'une 17.beta.-hydroxystéroïde-déshydrogénase (17.beta.-HSD) telle qu'une enzyme 17.beta.-HSD de type 1, de type 2 ou de type 3.

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