Therapeutically effective topical application of st1435

A - Human Necessities – 61 – K

Patent

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A61K 31/57 (2006.01) A61K 9/70 (2006.01) A61K 47/00 (2006.01)

Patent

CA 2083404

The progesterone analog ST1435 has now been found to attain therapeutically effective levels upon topical application to the skin. ST1435 can be administered topically either in liquid or semisolid base such as a cream or gel or in a solid base such as a transdermal device such as a disk, band patch or bracelet. The invention further provides topical applications suitable for transdermal delivery of therapeutically effective amounts of ST1435.

Il est prouvé maintenant que l'analogue de progestérone ST1435 atteint des niveaux thérapeutiquement efficaces par application topique sur la peau. Le ST1435 peut être administré topiquement soit par l'intermédiaire d'une base liquide ou semi-liquide, telle que crème ou gel, soit par l'intermédiaire d'une base solide, telle qu'un dispositif transdermique, par exemple un disque, un morceau de bande ou un bracelet. On décrit aussi des applications topiques convenant à l'administration transdermique de quantités thérapeutiquement efficaces de ST1435.

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