A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/564 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2230852
The present invention provides a novel method for the treatment of cellular accumulation in chronic inflammatory diseases such as rheumatoid arthritis. The method includes gene delivery and gene expression that is capable of enhancing apoptosis of accumulating cells and those cells which recruit accumulating cells. Also provided are diagnostic methods for detecting cellular accumulation diseases.
Nouvelle méthode pour traiter l'accumulation de cellules dans les maladies inflammatoires chroniques comme la polyarthrite rhumatoïde. La méthode fait appel à des mécanismes de transport et d'expression de gènes capables d'accroître l'apoptose des cellules qui s'accumulent et de celles qui les recrutent. Une méthode diagnostique permettant de détecter les maladies d'accumulation cellulaire est également décrite.
Firestein Gary S.
Green Douglas R.
Zvaifler Nathan J.
La Jolla Institute For Allergy And Immunology
Mbm Intellectual Property Law Llp
The Regents Of The University Of California
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