Therapy for tissue membrane insufficiency

Details Therapy for tissue membrane insufficiency Therapy for tissue membrane insufficiency

A - Human Necessities

61

K

A61K 31/715 (2006.01) A61K 31/70 (2006.01)

Patent

CA 2231989

Disclosed are methods of therapy applicable to pathologies that involve loss of integrity of tissue and organ membranes that lead to abnormal permeation of proteinic and other agents and their elimination or penetration of other anatomical functions. Such deficiencies are associated directly or indirectly, for example, with inflammatory diseases, with diabetes and others. The therapeutic method involves administering to the membrane in need of treatment of therapeutic amount of an oligosaccharide, preferably a cyclic oligosaccharide, having up to about 10 sugar units per molecule and having at least 1.4 anionic substituents per sugar unit. The anionic substituents are preferably the residues of strong acids.

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