Therapy of autoimmune disease in a patient with an...

Details Therapy of autoimmune disease in a patient with an... Therapy of autoimmune disease in a patient with an...

A - Human Necessities

61

K

A61K 39/395 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2519870

The present application describes therapy with antagonists which bind to B cell surface markers, such as CD20. In particular, the application describes the use of such antagonists to treat autoimmune disease in a mammal who experiences an inadequate response to a TNF-.alpha. inhibitor.

L'invention concerne un traitement à l'aide d'antagonistes qui se lient à des marqueurs de surface de cellules B, tels que CD20. Notamment, l'application décrit l'utilisation de ces antagonistes pour traiter une maladie auto-immune chez un mammifère qui présente une réponse inadéquate à un inhibiteur de TNF-.alpha..

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