Therapy using 1-aminocyclohexane derivatives for the...

A - Human Necessities – 61 – K

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A61K 31/13 (2006.01) A61K 31/445 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2556969

The present invention relates to the treatment of behavioral disorders, especially agitation, associated with a central nervous system (CNS) disorder, especially Alzheimer's disease (AD), cerebrovascular disease (VaD), or Down's Syndrome, in a mammal, comprising administering to said mammal an 1- aminocyclohexane, alone or in combination with a acetylcholinesterase inhibitor. In one embodiment, the 1-aminocyclohexane is memantine.

Traitement de troubles du comportement, en particulier de l'agitation, associés au système nerveux central (SNC), en particulier de la maladie d'Alzheimer, des maladies cérébrovasculaires ou de la trisomie 21, chez un mammifère, qui consiste à administrer à ce mammifère un 1-aminocyclohexane, seul ou en combinaison avec un inhibiteur d'acétylcholinestérase. Dans un mode de réalisation, le 1-aminocyclohexane est de la mémantine.

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