Therapy using cytokine inhibitors

Details Therapy using cytokine inhibitors Therapy using cytokine inhibitors

A - Human Necessities

61

K

A61K 31/395 (2006.01)

Patent

CA 2691214

The present invention relates to methods of treating, preventing, modifying and managing cytokine-mediated disorders or related disorders, which comprise the administration of a compound, such as a cytokine inhibitor, alone or in combination with known therapeutics. The invention also relates to pharmaceutical compositions and dosing regimens using the disclosed compounds. In particular, the invention relates to the use of compounds as disclosed herein, optionally in conjunction with other therapies, for the treatment of autoimmune diseases, inflammatory diseases, cardiovascular diseases, and cancer.

La présente invention concerne des procédés permettant de traiter, de prévenir, de modifier et de gérer des troubles induits par les cytokines ou des troubles associés, les procédés consistant à administrer un composé, tel qu'un inhibiteur de cytokine, seul ou combiné à des thérapeutiques connues. L'invention concerne également des compositions pharmaceutiques et des régimes posologiques utilisant les composés décrits. En particulier, l'invention concerne l'utilisation de composés tels qu'ils sont décrits dans ce document, éventuellement avec d'autres thérapies, pour le traitement de maladies auto-immunes, de maladies inflammatoires, de maladies cardiovasculaires, et du cancer.

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