Therapy via targeted delivery of nanoscale particles

A - Human Necessities – 61 – K

Patent

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Details

A61K 41/00 (2006.01) A61K 47/48 (2006.01) A61N 2/02 (2006.01) A61N 5/00 (2006.01) A61N 2/00 (2006.01) A61N 5/02 (2006.01)

Patent

CA 2515430

Methods for treating cells, diseased tissue, pathogens, or other undesirable matter involve the administration of a bioprobe (energy susceptive materials that are attached to a target-specific ligand) to a patient's body, body part, tissue, or body fluid (such as blood, blood plasma, or blood serum). An energy source provides energy to the bioprobe so as to destroy, rupture, or inactivate the target. Various energy forms, such as AMF, microwave, acoustic, or a combination thereof, created via a variety of mechamisms can be used. The disclosed methods may be useful in the treatment of a variety of indications, including, but not limited to, cancer of any type, such as bone marrow, lung, vascular, neuro, colon, ovarian, breast and prostate cancer, AIDS, adverse angiogenesis, restenosis, amyloidosis, tuberculosis, obesity, malaria, and illnesses due to viruses, such as HIV.

L'invention porte sur des méthodes de traitement de cellules, de tissu malade, d'agents pathogènes ou d'autres matières indésirables, ces méthodes consistant à administrer une biosonde (matériaux sensibles à l'énergie qui sont fixés à un ligand spécifique d'une cible) dans le corps d'un patient, dans une partie du corps, dans un tissu ou dans un fluide biologique (tel que le sang, le plasma sanguin ou le sérum sanguin). Une source d'énergie envoie l'énergie à la biosonde de façon à détruire, rompre ou inactiver la cible. Diverses formes d'énergie telles que le champ magnétique alternatif, l'hyperfréquence, l'énergie acoustique ou une combinaison de celles-ci peuvent être utiles dans le traitement de différents états tels que notamment, mais pas exclusivement, tous types de cancer tels que le cancer de la moelle osseuse, du poumon, du système vasculaire, du système nerveux central, du côlon, des ovaires, du sein et de la prostate, le SIDA, l'angiogenèse tumorale, la resténose, l'amyloïdose, la tuberculose, l'obésité, la malaria et les maladies dues à des virus tels que le VIH.

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