Thermal cycler for pcr including temperature control bladder

Details Thermal cycler for pcr including temperature control bladder Thermal cycler for pcr including temperature control bladder

B - Operations, Transporting

01

J

B01J 19/30 (2006.01)

Patent

CA 2697264

Methods and devices for performing chemical reactions under controlled temperature are described. In one embodiment, the devices provided by the invention comprise a housing diminished hold a reaction chamber disposed within an interior volume of the housing. The reaction chamber has thermally conductive interior and exterior surfaces defining an internal volume therein at a first temperature. The device also includes at least one temperature-control substance at a second temperature into said bladder and expel said temperature-control substance, the bladder expands to about substantially at least a portion of said exterior surfaces of said reaction chamber to enable thermal exchange between said temperature-control substance the said internal volume of reaction chamber.

L'invention concerne des procédés et des dispositifs pour effectuer des réactions chimiques sous une température commandée. Dans un mode de réalisation, les dispositifs prévus par l'invention comprennent un boîtier diminué d'une chambre de réaction disposée dans un volume intérieur du boîtier. La chambre de réaction a des surfaces intérieure et extérieure thermiquement conductrices définissant un volume intérieur à une première température. Le dispositif comprend aussi au moins une substance de commande de température à une seconde température dans la vessie et expulse la substance de commande de température, la vessie s'étend environ jusqu'à au moins sensiblement une partie des surfaces extérieures de la chambre de réaction pour permettre un échange thermique entre la substance de commande de température et le volume intérieur de la chambre de réaction.

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