A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/15 (2006.01)
Patent
CA 2698392
Methods of thermally inactivating a rotavirus are provided according to the present invention which include exposing the rotavirus to a temperature in the range of about 50°C - 80°C, inclusive, for an incubation time sufficient to render the rotavirus incapable of replication or infection. The thermally inactivated rotavirus is antigenic and retains a substantially intact rotavirus particle structure. Vaccine compositions and methods of vaccinating a subject against rotavirus are provided which include generation and use of thermally inactivated rotavirus.
L'invention concerne des procédés d'inactivation thermique d'un rotavirus, qui comprennent l'exposition du rotavirus à une température comprise dans l'intervalle d'environ 50 °C à 80 °C, compris, pendant une durée d'incubation suffisante pour rendre le rotavirus incapable de réplication ou d'infection. Le rotavirus thermiquement inactivé est antigénique et conserve une structure de particule de rotavirus sensiblement intacte. L'invention concerne également des compositions vaccinales et des procédés de vaccination d'un sujet contre un rotavirus, qui comprennent la production et l'utilisation d'un rotavirus thermiquement inactivé.
Glass Roger I.
Jiang Baoming
Saluzzo Jean-Francois
Department Of Health And Human Services The Government Of The United States Of America As Represented By
Ridout & Maybee Llp
LandOfFree
Thermal inactivation of rotavirus does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Thermal inactivation of rotavirus, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Thermal inactivation of rotavirus will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1779955