Thermodynamically stable form of bay 43-9006 tosylate

Details Thermodynamically stable form of bay 43-9006 tosylate Thermodynamically stable form of bay 43-9006 tosylate

C - Chemistry, Metallurgy

07

D

C07D 213/81 (2006.01) A61K 31/44 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2581843

The present invention relates to a novel form, thermodynamically stable at room temperature, of the tosylate salt of 4-{4-[({[4-chloro-3- (trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-N-methylpyridine-2- carboxamide, to processes for its preparation, to medicaments comprising it and to its use in the control of disorders.

La présente invention concerne une nouvelle forme thermodynamiquement stable à température ambiante du sels tosylate de 4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-N-methylpyridine-2-carboxamide. Cette invention concerne également des procédés permettant de préparer cette nouvelle forme, ainsi que des médicaments comprenant cette nouvelle forme et l'utilisation de ces médicaments pour traiter certains troubles.

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