Thermodynamics, design, and use of nucleic acid sequences

Details Thermodynamics, design, and use of nucleic acid sequences Thermodynamics, design, and use of nucleic acid sequences

C - Chemistry, Metallurgy

12

Q

C12Q 1/70 (2006.01) C12N 15/10 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2165163

A method of providing the sequence of a single stranded nucleic acid molecule, which, when hybridized to a complementary single stranded molecule, results in a double stranded (duplex) structure having a preselected value for a free energy parameter.

L'invention concerne une méthode utilisant la séquence d'une molécule d'acide nucléique simple brin qui, lorsqu'elle est hybridée à une molécule complémentaire simple brin, produit une structure double brin (duplex) ayant une valeur présélectionnée du paramètre énergie libre.

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