Thermoreversible oil-in-water emulsion

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/39 (2006.01) A61K 9/107 (2006.01) A61K 39/145 (2006.01) A61K 39/245 (2006.01) A61K 47/06 (2006.01) A61K 47/10 (2006.01) C07K 14/045 (2006.01) C07K 14/11 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2635724

The invention relates to a thermoreversible oil-in-water emulsion which comprises: a TLR4 agonist whose chemical structure does not include a sugar ring, squalene, a nonionic surfactant belonging to the polyoxyethylene alkyl ether chemical group, a hydrophilic surfactant and an aqueous solvent, and which exhibits immunostimulating properties.

L'invention se rapporte à une emulsion huile dans eau, thermoréversible, comprenant : un agoniste du TLR4 dont la structure chimique ne comporte pas de noyau sucré, du squalène, un tensioactif non ionique appartenant au groupe chimique des polyoxyethylène alkyl éther, un tensioactif hydrophile, un solvant aqueux, et qui manifeste des propriétés immunostimulantes.

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