Thermosensitive polymers for therapeutic use and methods of...

C - Chemistry – Metallurgy – 08 – F

Patent

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C08F 290/06 (2006.01) A61K 47/30 (2006.01) A61L 15/22 (2006.01) A61L 15/44 (2006.01) C08F 2/30 (2006.01) C08F 2/50 (2006.01) C12N 5/00 (2006.01) C12N 11/08 (2006.01)

Patent

CA 2531687

A process for preparing a thermosensitive polymer from a microemulsion is provided. The microemulsion comprises a monomer capable of forming a thermosensitive polymer and a polymerizable surfactant. Additional comonomers may be included in the microemulsion to vary the properties of the polymers produced. The resulting thermosensitive polymers may be nanoporous. The polymers according to the invention are suitable for use in medical applications, including use as a wound dressing and for delivery of cells to a graft site.

L'invention concerne un procédé permettant de préparer un polymère thermosensible à partir d'une microémulsion. Cette microémulsion contient un monomère capable de former un polymère thermosensible et un tensioactif polymérisable. Des comonomères additionnels peuvent être ajoutés à la microémulsion afin de modifier les propriétés des polymères produits. Les polymères thermosensibles résultants peuvent être nanoporeux. Le polymères décrits conviennent pour des applications médicales, notamment pour les pansements, et pour le transfert de cellules sur le site d'une greffe.

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