Thiadiazole antiviral agents

Details Thiadiazole antiviral agents Thiadiazole antiviral agents

C - Chemistry, Metallurgy

12

N

167/208, 195/46,

C12N 5/00 (2006.01) A01N 47/36 (2006.01) A01N 47/40 (2006.01) A01N 47/42 (2006.01) A01N 47/44 (2006.01) A61K 31/41 (2006.01) A61L 2/00 (2006.01) C07D 285/12 (2006.01) C07D 285/135 (2006.01)

Patent

CA 1307222

X-6675A ABSTRACT Compounds of formula (I) (I) Image wherein: R1 is hydrogen, and R2 is cyano, or -C(=S)-NH-R3; or R1 and R2 taken together are =C(NH2)2 or =C(R5)(NHR3'); R3 and R3' are hydrogen or -COOR4; R4 is C1-C10 alkyl, substituted C1-C10 alkyl, C2-C10 alkenyl, substituted C2-C10 alkenyl, phenyl, or substituted phenyl; and R5 is hydrogen or -S-R6 where R6 is C1-C4 alkyl, cyano-C1-C4 alkyl or pyridyl-C1-C4 alkyl, and salts thereof, are useful antiviral agents.

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