Thiadiazoline derivatives

Details Thiadiazoline derivatives Thiadiazoline derivatives

C - Chemistry, Metallurgy

07

D

C07D 285/12 (2006.01) A61K 31/433 (2006.01) A61K 31/4439 (2006.01) A61K 31/497 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01) C07D 417/04 (2006.01) C07D 417/06 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2542034

Antitumor agents containing as the active ingredient thiadiazoline derivatives represented by the general formula (I) or pharmacologically acceptable salts thereof: (I) wherein Z is sulfur or the like; R1 is substituted or unsubstituted lower alkynyl or the like; R2 is hydrogen or the like; R3 is substituted or unsubstituted lower alkyl or the like; and R4 is substituted or unsubstituted aryl or the like.

L'invention concerne des agents antitumoraux contenant comme principe actif des dérivés de thiadiazoline, représentés par la formule générale (I) ou leurs sels pharmaceutiquement acceptables. Dans cette formule (I), Z désigne soufre ou similaire ; R?1¿ désigne alkynyle inférieur substitué ou non substitué ou similaire ; R¿2? désigne hydrogène ou similaire ; R?3¿ désigne alkyle inférieur substitué ou non substitué ou similaire ; et R?4¿ désigne aryle substitué ou non substitué ou similaire.

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