Thiazole compounds as cannabinoid receptor ligands and uses...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 417/06 (2006.01) A61K 31/425 (2006.01) C07D 277/46 (2006.01) C07D 513/04 (2006.01)

Patent

CA 2647597

The present invention relates to compounds of formula (I), or pharmaceutical salts, prodrugs, salts of prodrugs, or combinations thereof, wherein R1, R2, R3, R4, and L1 are defined in the specfication, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions. The present invention also relates to compounds of formula (II), or pharmaceutical salts, prodrugs, salts of prodrugs, or combinations thereof, wherein R1a, R2a and (Rx)n are as defined in the specification, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.

La présente invention concerne des composés de formule (I) ou des sels pharmaceutiques, des promédicaments, des sels de promédicaments ou des associations de ceux-ci, formule dans laquelle R1, R2, R3, R4 et L1 sont tels que définis dans la description; des compositions comprenant de tels composés; et des procédés de traitement d'affections et de troubles utilisant de tels composés et compositions. La présente invention concerne également des composés de formule (II) ou des sels pharmaceutiques, des promédicaments, des sels de promédicaments ou des associations de ceux-ci, formule dans laquelle R1a, R2a et (Rx)n sont tels que définis dans la description; des compositions comprenant de tels composés; et des procédés de traitement d'affections et de troubles utilisant de tels composés et compositions.

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