Thiazole compounds, processes for the preparation thereof...

Details Thiazole compounds, processes for the preparation thereof... Thiazole compounds, processes for the preparation thereof...

C - Chemistry, Metallurgy

07

D

167/211, 167/234

C07D 277/20 (2006.01) A61K 31/395 (2006.01) C07D 277/28 (2006.01) C07D 277/40 (2006.01) C07D 417/12 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2012716

ABSTRACT There are described compounds of the formula: Image (I) wherein A is lower alkylene or carbonyl, R1 and R2 are each halogen, lower alkyloxy, lower alkylthio or lower alkylsulfinyl, R3 is amino-protective group, and R4 is hydrogen, lower alkyl which may have heterocyclic group, piperidyl which may have suitable substituent(s), amidino or amino-protective group, and pharmaceutically acceptable salts thereof. The preparation of these compounds, pharmaceutical composition containing same, and their use in treating diseases are also disclosed. These compounds can be used for the treatment of thrombosis, hypertension, cardiovascular or cerebrovascular diseases, allergy and inflammation, particularly thrombosis, in human beings and animals.

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