Thiazole derivatives

Details Thiazole derivatives Thiazole derivatives

C - Chemistry, Metallurgy

07

D

260/104.1, 260/3

C07D 277/42 (2006.01) C07D 417/12 (2006.01) C07D 501/46 (2006.01)

Patent

CA 1244823

Abstract A novel aminothiazoleacetic acid derivative which is an advantageous synthetic intermediate for .beta.-lactam antibiotics, and its production method and use. Starting with diketene, the production method comprises the following sequence of steps. halogenation Diketene ? 4-haloacetoacetyl halide Image (In the above formulas, R is lower alkyl or phenyl; R1 and R2 each are hydrogen or lower alkyl; X and X' each are halogen; W is S or SO2; and W' is OH or Image )

444818

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