Thiazole derivatives, processes for the preparation thereof...

C - Chemistry – Metallurgy – 07 – D

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C07D 277/20 (2006.01) C07C 45/00 (2006.01) C07D 277/22 (2006.01) C07D 277/28 (2006.01) C07D 277/40 (2006.01) C07D 277/42 (2006.01) C07D 277/46 (2006.01) C07D 277/48 (2006.01) C07D 277/50 (2006.01) C07D 417/02 (2006.01)

Patent

CA 1154764

ABSTRACT OF THE DISCLOSURE Thiazole derivatives and their process of prepara- tion are provided having: Image (I) wherein R1 is hydrogen, amino, or mono- or di- substituted amino, in which the substitutent is selected from lower alkyl. acyl and di(lower)alkylaminomethylene, R2 is hydrogen. halogen, lower alkyl or aryl. R3 is ar(lower)alkyl optionally substituted by halogen, A is lower alkylene optionally interrupted by a sulfur atom, and Y is C1-C3alkylene, and their pharmaceutically acceptable salts, the derivatives have antiallergic activities and can be used in the treatment of allegic symptoms.

367494

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