Thiazolidine compounds, their preparation and their...

C - Chemistry – Metallurgy – 07 – D

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C07D 277/34 (2006.01) A61K 31/425 (2006.01) A61K 31/435 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2086277

1983 ABSTRACT OF THE DISCLOSURE Compounds of formula (I): Image (I) (wherein: R1 is alkyl; R2 and R3 are each alkyl or alkoxy, or R2 and R3 together form an optionally substituted benzene ring, and, when R2 and R3 together form said benzene ring, R1 is hydrogen, halogen or alkyl; R4 and R5 are hydrogen, or R4 and R5 together represent a single carbon-carbon bond; Y1 and Y2 are each hydrogen, alkyl, acyl, or optionally substituted benzoyl, naphthoyl, pyridine- carbonyl or quinolinecarbonyl group; W is a single bond or alkylene; and Z is hydrogen or a cation) have valuable therapeutic and prophylactic activities, including anti-diabetic activities.

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