Thiazolidine derivatives for the treatment of psoriasis

Details Thiazolidine derivatives for the treatment of psoriasis Thiazolidine derivatives for the treatment of psoriasis

A - Human Necessities

61

K

A61K 31/425 (2006.01) A61K 31/426 (2006.01) A61K 31/427 (2006.01) A61K 31/44 (2006.01) A61K 31/4439 (2006.01) A61K 31/47 (2006.01) A61K 31/4709 (2006.01)

Patent

CA 2193493

A new medical use for certain thiazolidine derivatives is disclosed. Specifically, treatment of hyperproliferative epithelial cell conditions, such as psoriasis, by administration of thiazolidinediones or 5'- aryl substituted thiazolidine derivatives is described. Appropriate chemical structures, synthetic reactions, formulations, routes of administration and dosages are included.

Nouvelle utilisation médicale de certains dérivés de thiazolidine portant spécifiquement sur le traitement d'états d'hyperprolifération des cellules épithéliales tels que le psoriasis, et consistant à administrer des thiazolidinediones ou des dérivés de la thiazolidine à substitution 5'-aryle. L'invention porte également sur les structures chimiques appropriées, sur les réactions de synthèse, sur les voies d'administration et sur les dosages.

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