Thiazolidinones, production and use thereof as medicaments

Details Thiazolidinones, production and use thereof as medicaments Thiazolidinones, production and use thereof as medicaments

C - Chemistry, Metallurgy

07

D

C07D 277/34 (2006.01) A61K 31/426 (2006.01) A61K 31/427 (2006.01) A61P 35/00 (2006.01) C07D 417/06 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2544267

The invention relates to thiazolidinones of general formula ( I ), wherein Q, A, B, X, R1 and R2 have the meaning cited in the description, and the general formula (IA) wherein Q, A, B, X, R1 and R2a have the meaning cited in the description, to the production and use thereof as inhibitors of the Polo Like Kinase (PLK) for the treatment of different diseases. The invention also relates to intermediate products for the production of thiazolidinones.

L'invention concerne des thiazolidinones de formule ( I ), dans laquelle Q, A, B, X, R?1¿ et R?2¿ ont les significations indiquées dans la description, et de formule (IA), dans laquelle Q, A, B, X, R?1¿ et R?2a¿ ont les significations indiquées dans la description, ainsi que leur production et leur utilisation comme inhibiteurs de la Polo Like Kinase (PLK) pour traiter différentes maladies. La présente invention porte également sur des produits intermédiaires pour réaliser ces thiazolidinones.

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