Thiazoline derivatives, process for the preparation and...

Details Thiazoline derivatives, process for the preparation and... Thiazoline derivatives, process for the preparation and...

C - Chemistry, Metallurgy

07

D

167/231, 167/234

C07D 277/08 (2006.01) A61K 31/425 (2006.01) C07D 277/10 (2006.01) C07D 277/18 (2006.01) C07D 307/52 (2006.01) C07D 417/06 (2006.01)

Patent

CA 1273933

ABSTRACT OF THE DISCLOSURE New thiazolidine compounds of the formula (I) having anti-ulcer activity are disclosed: Image (I) wherein Ar is a 2-furyl or a phenyl, naphthyl or pyridyl group optionally substituted by one or more halogen atoms, one or more C1-4-alkyl, C1-6-alkoxy, halogen-C1-4-alkoxy, dihalomethyl, trihalomethyl, hydroxyl or nitro groups or by a group of the formula (II), Image (II) wherein Y is nitrogen or CH; Z is cyano or carbamoyl if Y is nitrogen, and represents a nitro group if Y is CH. Also disclosed are several processes for preparing the new compounds as well as pharmaceutical compositions and method of treatment employing same.

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