Thiazolopyridinone derivates as mch receptor antagonists

C - Chemistry – Metallurgy – 07 – D

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C07D 513/04 (2006.01) A61K 31/435 (2006.01) A61P 3/00 (2006.01)

Patent

CA 2589695

The present invention relates to a melanin concentrating hormone antagonist compound of formula (I); wherein w, R1, q, p, R2, t, Ar1, L1, R3 and R4 are as defined, or a pharmaceutically acceptable salt, solvate, or enantiomer thereof useful in the treatment, prevention or amelioration of symptoms associated with obesity and related diseases.

La présente invention concerne un composé antagoniste de l'hormone concentrant la mélanine, de formule (I) ; où w, R1, q, p, R2, t, Ar1, L1, R3 et R4 sont tels que définis dans la présente invention, ou un sel, un solvate, ou un énantiomère de qualité pharmaceutique dudit composé. Ledit composé et ses dérivés peuvent être employés dans le traitement, la prévention ou le soulagement de symptômes associés à l'obésité et aux maladies qui lui sont liées.

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