C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 495/04 (2006.01) A61K 31/4365 (2006.01) A61P 9/10 (2006.01) A61P 13/12 (2006.01) A61P 19/10 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2502614
This invention provides compounds of Formula (1 a) - (1f) wherein:X, R1, and R2 are defined hereinbefore in the specification, which are useful in the treatment of cancer, stroke, osteoporosis, polycystic kidney disease, autoimmune disease, rheumatoid arthritis, and transplant rejection and process for producing said compounds.
L'invention concerne des composés représentés par la formule (1a) (1f). Dans ces formules, X, R?1¿, et R?2¿ sont tels que définis dans la description. Ces composés sont utiles dans le traitement du cancer, d'accidents vasculaires cérébraux, de l'ostéoporose, de la maladie polykystique des reins, de maladies auto-immunes, de la polyarthrite rhumatoïde, et de rejets de transplantation. L'invention concerne également un procédé de production de ces composés.
Barrios Sosa Ana Carolina
Boschelli Diane Harris
Durutlic Haris
Wu Biqi
Zhang Nan
Torys Llp
Wyeth
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