Thieno[3,2-b]pyridine derivatives

Details Thieno[3,2-b]pyridine derivatives Thieno[3,2-b]pyridine derivatives

C - Chemistry, Metallurgy

07

D

C07D 519/00 (2006.01) A61K 31/435 (2006.01)

Patent

CA 2091506

The thieno[3.2-b]pyridine derivative of the present invention promotes the gastric emptying in male ddy mice and the gastric contraction in dogs sutured with a strain-gauge transducer. It is believed that the derivative has the action to enhance gastric motor action and gastric emptying. Therefore, the compound of the present invention is effective for the prevention and therapeutical treatment of the symptoms caused by gastric hypanakinesis, such as heartburn, abdominal distension feeling, anorexia, unpleasant feeling on upper abdomen, abdominalgia, nausea, vomiting, etc. caused by the underlying diseases such as acute and chronic gastritis, stomach and duodenum ulcer, gastroneurosis, gastroptosis, etc. The present invention also encompasses a pharmaceutical composition containing as the effective ingredient the compound of the present invention, and a method for producing the same.

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