Thienopyridazinones and their use in modulation of...

C - Chemistry – Metallurgy – 07 – D

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C07D 495/04 (2006.01) A61K 31/519 (2006.01) A61P 37/02 (2006.01)

Patent

CA 2512136

The invention relates to thienopyridazinones compound of formula (I) wherein: R1, R2 and Q are as defined in the specification, and Ar and Ar2 are selected from certain aromatic ring systems which may be optionally substituted, as defined in the specification. Processes for the preparation of compounds of formula (I), pharmaceutical compositions containing them and their use in therapy is also described and claimed.

La présente invention concerne des composés de thiénopyridazinones représentés par la formule (I) dans laquelle: R?1¿,?¿R?2¿ et Q sont tels que définis dans la spécification, et Ar et Ar?2¿ sont choisi parmi certains systèmes cycliques aromatiques éventuellement substitués conformément aux définitions de la spécification. L'invention concerne également des procédés portant sur l'élaboration des composés représentés par la formule (I), des compositions pharmaceutiques à base de ces composés, et leur utilisation thérapeutique.

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