C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 495/04 (2006.01) A61K 31/4365 (2006.01) A61K 31/4545 (2006.01) A61K 31/4725 (2006.01) A61K 31/496 (2006.01) A61K 31/5377 (2006.01) A61K 31/541 (2006.01) A61K 31/55 (2006.01) A61K 31/551 (2006.01) A61K 31/553 (2006.01) A61K 31/554 (2006.01) A61P 19/02 (2006.01) A61P 19/08 (2006.01) A61P 19/10 (2006.01) A61P 29/00 (2006.01)
Patent
CA 2562827
The invention provides osteogenesis-promoting compounds, namely, compounds represented by the general formula (I) and pharmacologically acceptable salts thereof: wherein R1 is H or alkyl; R2 is RaS-, RaO-, RaNH-, Ra(Rb)N-, or cyclic amino; and Ra and Rb are each optionally substituted alkyl, optionally substituted cycloalkyl, or the like.
L~invention fournie des composés promoteurs d'ostéogènes, à savoir, les composés représentés par la formule générale (I) et les sels-ci pharmacologiquement acceptés: (I) dans lequel R?1¿ est H ou alkyl; R?2¿ is R?a¿S-, R?a¿O-, R?a¿NH-, R?a¿(R?b¿)N-, ou cyclic amino; et R?a¿ et R?b ¿sont chacun un substitut optionnel d~alkyl, un substitut optionnel de cycloalkyl ou similaire.
Matsui Satoshi
Naito Satoru
Nakao Akira
Oizumi Kiyoshi
Shimada Kousei
Marks & Clerk
Sankyo Company Limited
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