C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/211, 260/246
C07D 495/04 (2006.01) C07D 333/36 (2006.01)
Patent
CA 1240997
Louis GIRAL, Marc PUYGRENIER and Jacques BOMPART NOVEL THIENOPYRIDINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM. ABSTRACT OF THE DISCLOSURE Thienopyridinone derivatives of the general formula : Image in which Y represents hydrogen or a lower alkyl group and X represents : - a hydroxy, lower alkanoyloxy, lower alkoxy unsubstituted or substituted by a hydroxy, lower alkoxy, di-(lower alkyl)-amino, piperidino, pyrrolidino, morpholino or N-(lower alkyl)- piperazino group, - a group of formula : Image in which R' and R", which are the same or different, each represent hydrogen or a lower alkyl, W represents hydrogen or a lower alkyl radical or a vinyl or ethynyl group and Z represents hydrogen or a lower alkyl radical, - a phenyl radical unsubstituted or substituted by an atom of fluorine, chlorine, bromine or iodine or by a hydroxy, lower alkoxy or nitro group, - a group of formula : Image in which Z has the same meaning as above, - an amino, lower alkylamino or -NHCOOZ group in which Z has the same meaning as above and pharmaceutically acceptable salts thereof. They possess antibactericidal properties.
480734
Bompart Jacques
Giral Louis
Puygrenier Marc
Robic Robic & Associes/associates
Sanofi
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