Thienopyridone derivatives as amp-activated protein kinase...

C - Chemistry – Metallurgy – 07 – D

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C07D 333/38 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2723429

The present invention relates to compounds of formula (I) wherein R1, R2 and B1, B2 are as defined in claim 1, including pharmaceutical compositions thereof and for their use in the treatment and/or prevention of diseases and disorders modulated by AMP agonists. The invention is also directed to intermediates and to a method of preparation of compounds of formula (I).

La présente invention concerne des composés de formule (I) dans laquelle R1, R2 et B1, B2 sont tels que définis dans la revendication 1, des compositions pharmaceutiques les contenant et leur utilisation dans le traitement et/ou la prévention de maladies et pathologies modulées par les agonistes de lAMP. Linvention concerne également des intermédiaires et un procédé de préparation des composés de formule (I).

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