Thienopyridones

Details Thienopyridones Thienopyridones

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) A61K 31/435 (2006.01)

Patent

CA 2165129

Thienopyridone derivatives of the formula I Image I in which B is CH or N, Image is Image , Image or Image , R is H, Image , Image or Image , R1, R2 and R5 are in each case E, A or Hal, R3 and R4 are in each case H, A, OH, OA, Hal, CF3, NO2, NH2, NHA, N(A)2 or NHAc, R6 is H or Hal, X is -CH2-, -CO-, -O-, -NH-, -NA- or -S-, A is alkyl having 1-4 carbon atoms, Ac is alkanoyl having 1-6 carbon atoms, or benzoyl and Hal is F, Cl, Br or I, and their salts, exhibit a high affinity for binding sites of amino acid receptors and are therefore suitable for treating neurodegenerative diseases.

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