Thienopyrimidine derivatives as phosphodiesterase 10 inhibitors

Details Thienopyrimidine derivatives as phosphodiesterase 10 inhibitors Thienopyrimidine derivatives as phosphodiesterase 10 inhibitors

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) A61K 31/495 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2594676

Certain thienopyrimidine derivatives are useful for the inhibition of PDE10 enzymes, and thus are useful for treating psychiatric or neurological syndromes, e.g., pyschoses, obsessive-compulsive disorder and/or Parkinson's disease, as well as, for example, treating a disease state modulated by PDE10 activity.

La présente invention concerne certains dérivés de la thiénopyrimidine utiles pour l~inhibition des enzymes PDE 10, et donc pour le traitement de syndromes psychiatriques ou neurologiques tels que les psychoses, les troubles obsessionnels compulsifs et/ou la maladie de Parkinson ainsi que, par exemple, pour le traitement d~états pathologiques régulés par l~activité de PDE10.

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